통합 검색

통합 검색

최성경 (Sung Kyung Choi)

Ph. D


* Postdoc : 2020.03 ~

* MS-PhD : 2014.09 ~ 2020.02 Konkuk University School of Medicine


Research Keywords

Chromatin remodeler, SWI/SNF complex, HELLS, Mitochondria dynamics, Histone modification


Research Focus

- Nuclear–mitochondrial communication

- Mitochondrial dynamics & metabolic signaling in cancer


Thesis

- (The) role of epigenetic modulators in cancer and during human EMT. 2020 Feb


Publications

- HELLS controls mitochondrial dynamics and genome stability in liver cancer by collusion with MIEF1. Cell Death Dis. 2025 Apr 2;16(1):239

- αKG-induced oxidative stress and mTOR inhibition as a therapeutic strategy for liver cancer. Medical Oncology. 2025 Mar 13;42(4):105

유빛누리 (Bitnuri Yu)

MS-Ph. D course


* MS-PhD : 2022.09 ~ 

* Intern : 2022.01 ~ 2022.08 Konkuk University School of Medicine


Research Keywords

RNA polymerase II & III, RN7SK, P-TEFb, POLR3G, Linker histone H1.5, Chromatin accessibility


Research Focus

- Cross-talk RNA polymerase II & III

- POLR3G-Driven Chromatin Remodeling

최태욱 (Tae Wook Choi)

MS-Ph. D course


* MS-PhD : 2025.01 ~


Research Keywords

RNA polymerase III, HeLa, SREBP2, Cholesterol biosynthesis


Research Focus

- The relationship between POLR3G and cholesterol homeostasis

- Regulation of cholesterol biosynthesis by SREBP2

정영훈 (Young Hoon Jung)

MS course


* MS : 2026.01 ~


Research Keywords

Polyamines, Liver Fibrosis, Liver cancer, Fibrosis reversibility


이녕찬 (Nyeong Chan Lee)

MS course


* MS : 2026.09 ~


Research Keywords

Liver cancer metastasis

Alumni

홍성휘 (Seong Hwi Hong)

Ph. D


Thesis

- Underlying mechanism of dysregulated epigenetic reader BRD4 and ATP dependent chromatin remodeler subunit SMARCB1 in liver cancer and esophageal squamous cell carcinoma (ESCC) 2019 Aug


Publications

- Nucleoporin 210 Serves a Key Scaffold for SMARCB1 in Liver Cancer. Cancer Res. 2021 Jan 15;81(2):356-370.

- SOX9 is controlled by the BRD4 inhibitor JQ1 via multiple regulation mechanisms. Biochem Biophys Res Commun. 2019 Apr 16;511(4):746-752.

김명준 (Myoung Jun Kim)

Ph. D


* Postdoc : 2022.03 ~ 2025.12 Konkuk University School of Medicine

* MS-PhD : 2016.09 ~ 2022.02 Konkuk University School of Medicine

* Intern : 2015.12 ~ 2016.08 Konkuk University School of Medicine


Research Keywords

RNA polymerase III, Osteoclastogenesis, Mitochondria, chromatin remodeler, EMT


Research Focus

- RNA polymerase II–III crosstalk in gene regulation and cell fate in cancer

- Chromatin remodeler & mitochondrial homeostatsis in oteoclastogenesis

- Role of RNA polymerase III in osteoclastogenesis


Thesis

- Epigenetic Approaches Challenged in Cellular Metamorphosis via non-histone acetylation, Metabolism-related O-GlcNAcylation, and Chromatin Accessibility. 2022 Feb


Publications

- Hells protects mitochondrial integrity via Nr2f2 suppression during osteoclast differentiation. Cell Commun Signal (2026).

- Hexosamine Biosynthetic Pathway-Derived O-GlcNAcylation Is Critical for RANKL-Mediated Osteoclast Differentiation. Int. J. Mol. Sci. 2021, 22, 8888.

- Oncogenic IL7R is downregulated by histone deacetylase inhibitor in esophageal squamous cell carcinoma via modulation of acetylated FOXO1. International Journal of Oncology 53, no. 1 (2018): 395-403.

이상용 (Sangyong Lee)

Ph. D


Thesis

- Epigenetic landscape analysis during RANKL-mediated osteoclast differentiation (Doctor).  2023. Feb

- (The) effects of α-ketoglutarate, a glutamine derived metabolite, on RANKL-mediated osteoclast differentiation (Master)



Publications

- Epigenetic landscape analysis reveals the significance of early reduced chromatin accessibility in osteoclastogenesis. Bone. 2023 Dec;177:116918.

- Glutamine metabolite α-ketoglutarate acts as an epigenetic co-factor to interfere with osteoclast differentiation. Bone. 2021 Apr;145:115836.

안설이 (Seor I Ahn)

MS


Thesis

- Crosstalk between Mitochondria and Nucleus in Mitochondrial Division Inhibitor Mdivi-1 treated SH-SY5Y cells. 2023 Feb



Publications

- Mdivi-1: Effective but complex mitochondrial fission inhibitor. Biochem Biophys Res Commun. 2024 May 28;710:149886.

김민호 (Minho Kim)

MS


* MS : 2024.01 ~ 2026.08 Konkuk University School of Medicine

* Intern : 2023.01 ~ 2023.12 Konkuk University School of Medicine


Research Keywords

SWI/SNF complex, SMARCB1, Ubiquitination, Hypoxia, POLR3G, Alternative splicing


Research Focus

- Regulation of protein stability through deubiquitination

- Alternative splicing in Osteoclast


Thesis

- USP21-mediated SMARCB1 stabilization under hypoxia may influence tumor progression and immune response in Hepatocellular carcinoma. 2026 Aug


Publications

- USP21-mediated SMARCB1 stabilization under hypoxia may influence tumor progression and immune response in HCC. Biochem Biophys Res Commun. 2026 Mar 19;805;153383